What Are Some Deadly Drug Combinations?

Dangerous drug combinations have become a common cause of death thanks to the increasing popularity of opioids and other drugs. Thousands of people die every year due to drug overdose across the U.S. every year. Symptoms of drug overdose depend on the combination being used with or without the help of pill reminder app. However, respiratory failure, coma, and reduced heartbeat are common indicators that you might be using the wrong combination. If not curbed in time, the user will die as a result.

Naloxone, which is an opioid reversal drug can be administered to cancel out effects of an overdose. But if combination involves non-opioids, naloxone will not be as effective. This makes drug-mixing even more dangerous.

With that in mind, we’ve discussed here a few fatal drug combos that take thousands of lives each year around the world.

Drug/Drug Interactions

In the modern age, it’s very common for patients to be taking multiple medications at a time. But this has increased the possibility of drug interactions and more drug combinations are in use than ever. Remember that drug/drug combo can weaken the effectiveness of other drugs, and can result in severe side effects.

To prevent these interactions, electronic prescribing was invented, with the goal that software would warn clinicians about dangerous combinations between one or more drugs that their patients were taking. But specialists cannot solely rely on this technology to prevent all drug to drug interactions. They must use their personal knowledge too to ensure patients’ safety.

Clarithromycin and Calcium-Channel Blockers

The combination of Clarithromycin with calcium-channel blockers can cause problems like hypotension and acute renal failure. Some other drugs that can be fatal when taken in combination with clarithromycin include:

  • Statins
  • Colchicine
  • Glipizide or glyburide

Alcohol and Benzodiazepines

Alcohol and benzodiazepines such as Xanax or Valium boost each other’s effects. The main goal of benzodiazepines is to reduce anxiety and produce a calming effect in the user. Benzodiazepines also reduce alcohol tolerance, so when taken with alcohol using prescription reminder app, the effects of both alcohol and benzos become more potent. This can be very dangerous because alcohol can maximize the effect of these drugs and causes increased blackouts. On the other hand, benzo medicines will interact in the same way with alcohol, causing memory issues and leading you to drink more than you realize.

Gray Death

Gray death is a mixture of drugs combined to produce an effect stronger than heroin. The deadly combination includes heroin, fentanyl, carfentanil, and an opiate called U-47700. It may include other drugs as well. Gray death is so strong that it could kill you instantly. And the fact that its several times more potent than morphine increases the possibility of overdose, making it extremely dangerous for your wellbeing.

Warfarin and Acetaminophen

Warfarin and acetaminophen form a very interesting combination. Many specialists are still unaware of the fact that using acetaminophen increases the international normalized ratio (INR). They recommend these drugs without considering their possible side effects.

Patients on regular warfarin and acetaminophen require close monitoring and should be tested for INR at least once a week. But those with occasional acetaminophen administration don’t really need that test.

When there is an unexpected jump in INR of a warfarin patient, it is worth asking if they are taking acetaminophen. Also, creating awareness among patients about acetaminophen and INR can avoid unwanted adjustments of warfarin doses.

A slight INR increase is fine for a while, but when a patient is on another drug that increases INR, specialists should make recommendations carefully.

Antidepressants and Ecstasy

Antidepressants when joined with ecstasy form one of the deadliest drug combinations ever.

Ecstasy increases serotonin levels in the brain while antidepressants impair its effect, leading the user to take more and more ecstasy to achieve euphoric effects.

Though you may not feel high when taking the two drugs together, your system will still be affected by their interaction. You may feel relatively sober as a result. But your body will suffer from overdose symptoms.

When serotonin levels get too high, serious conditions can occur such as shock, stroke, coma and even death.

Alcohol and Cocaine

This combination is extremely dangerous. Drinking alcoholic beverages in combination with cocaine can stress your liver to a point that it creates a byproduct called cocaethylene. This products obstructs the body’s ability to process toxic substances resulting in overdose which may lead to heart failure, hospitalization, or even death.

Remember that individuals with substance abuse issues aren’t the only one that are affected by this combination. Casual users can be as easily affected by it as those with a persistent habit.

Alcohol and Opiates

Opiates are pain medications which are being prescribed at alarmingly high rates. The biggest concern with their growing popularity is that their consequences are often ignored.

Opiates dull one’s nervous system to treat pain. But if abused, these medications can have awful effects on bodies. For example, their combination with alcohol is a frightening one because it slows down your respiration and impairs your coughing ability, making it extremely difficult to expel phlegm and other fluids. As a result, you may end up experiencing respiratory failure leading to hospitalization or even death.

Is There A Way to Avoid These Deadly Drug Combinations?

Due to the secret nature of drug abuse and addiction, very little safety information is available to drug users. Also, the non-regulation of drugs on the street increases the risk of accidental overdose . However, if you are currently experiencing issues with drug addiction, help isn’t far away. Contact one of the specialists in your area to make sure that the drug combinations you are taking using free medication reminder app don’t add up to your existing health issues.

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